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Case #1: Single Pulmonary Nodule (Lung
Cancer) |
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The initial chest x-ray on this 63-yr. old
smoker demonstrated a nodule in the right lung. A PET scan
was done showing increased metabolic activity indicative
of a malignancy (cancer). The PET scan showed that there
was no evidence of spread of the cancer to other parts of
the body. Surgery was performed as a result which revealed
a non-small cell carcinoma. |
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Case
#2: Solitary Pulmonary Nodule (Lung Cancer) |
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The arrow points to a lung nodule which has
increased glucose (sugar) metabolism, indicating that this
has a high likelihood of being a malignancy (cancer).
Active infections like T.B. may also be a possibility as
they also show high glucose metabolism. The other areas of
high activity such as the brain and bladder (dark purple
areas) do not indicate malignancies, but a high activity
of glucose accumulation which is normal functioning for
those body organs. |
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Case
#3: Brain Tumor |
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This
53-yr. old woman diagnosed with a highly malignant brain
tumor, gliobalstoma multiforme, had radiation treatment.
The darker area on the initial scan (lower right side)
reveals damage to the brain resulting from surgery and
radiation therapy. The second scan taken 6 months later,
shows there was recurrent cancer (arrow). Based on the
second scan, the patient then went back in for further
therapy. |
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Case #4:
Breast Cancer |
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Top PET scan shows resolution of the tumor within axillary
(armpit) lymph nodes (arrow). Another PET scan was taken
after chemotherapy (bottom scan), showing the absence of any tumor.
The dark areas above the raised arms in bottom picture is the
bone marrow.
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Case
#5: Recurrent Colon Cancer, Rising CEA |
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This
57-year old man had a colon cancer removed 1 year ago. On
a recent blood test, a tumor marker (CEA) was elevated. An
abdominal CT scan was negative except for a “cyst” in the
left lobe of the liver. The PET scan showed increased
glucose metabolism in this “cyst” indicating that this was
a malignancy (dark spot in left side of body). This was
successfully removed during surgery.
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In
detecting colon cancer, PET has a 95% accuracy rate versus
CT which is 68% accurate. |
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Case #6: Radioablation (radio waves
used to kill cancer) of Colon Cancer |
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The
top picture on the left shows a 50-yr old man with colon
cancer who had a metastasis in the liver (cancer has
spread from the colon, to the liver). Radioablation
(treatment of the cancer using radiowaves) was performed,
killing almost all the cancer except for a small nodule
(arrow on the bottom picture). Using PET, once this
small nodule was diagnosed, it was subsequently treated. |
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Case
#7: Middle aged man with lymphoma |
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The
first PET scan was done for staging (determining the
extent of cancer spread) and showed lymphoma in the neck,
chest, abdomen, spleen, and pelvis (arrows in top
picture). Following chemotherapy, a second PET scan was
done to evaluate therapeutic response 6 months later. It
showed no viable lymphoma (top picture) consistent with
a successful response to treatment. |
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Case
#8: Low Grade Non-Hodgkin’s Lymphoma |
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The
initial PET Scan (top picture to the left) demonstrates large masses in the
abdomen (bottom picture). One and a half years
later, another PET scan was taken showing that there is no
cancer evident after chemotherapy (the activity on the
later scan in the pelvis shows no cancerous activity). |
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Case #9: Esophageal Cancer
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This
60-year old male developed difficulty swallowing. Upon
endoscopic examination, a mass was seen in the lower
esophagus, where it joins the stomach. The biopsy showed
this mass to be cancer. The PET scan was used to see if
there had been any distant spread of the cancer to the
liver, chest, or abdomen. Since there was no spread,
surgery for complete removal was performed, rather than a
simple alleviation of the obstruction |
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Case
#10: Metastatic Esophageal Cancer |
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The top
PET scan shows that there is spread of the esophageal
cancer to a lymph node in the base of the left neck (top
of picture). The PET scan on the bottom shows that the
cancer also involves the stomach. |
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Case #11:
Myocardial Viability (Heart) |
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This
60-year old man with chronic heart failure following
severe heart attacks was being considered for open heart
surgery to place grafts to alleviate blocked arteries.
Because his heart was extremely weak and was only pumping
20% of the blood in the heart with each beat (normal is
greater than 50%), he was a high risk for surgery. The
surgeon needed to know if there was sufficient living
heart muscle to place bypass grafts, to restore blood flow
to the muscle, and produce a better heart squeeze. |
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The
inferior wall was thought to be dead, but with PET, which
has the ability to determine cell metabolism, we can see
good glucose metabolism and therefore, living heart muscle
(represented by the bright orange color). As a result of
using PET, the patient underwent surgery and has improved
his activity levels dramatically. |
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Case #12: Zevalin Therapy |
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Click here for detail information |
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here for PDF file reader |
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